Cell photographer, mixed media artist
At the cutting edge of science there is discovery, inspiration and many more questions than answers. We understand how to grow certain types of cells in a dish, like neurons, but do not yet know how we can use this power to solve problems of disease. The public tends to fill up the void between the known and the unknown with wonder, hope, expectations and misunderstandings. In the mind of the public, we have already solved the challenge of regeneration with the discovery of stem cells, but in reality there is much more work to be done.
Over the past decade, cell and molecular biologists have discovered the secrets of nuclear reprogramming. Essentially, we have learned how to ‘turn the clock back’ on the nucleus of a fully differentiated cell, changing it into a stem cell. The implications of this discovery are astounding and this series represents the progression to this moment, showing neural differentiation from different cells of origin: neural stem cells from the adult mouse brain, human embryonic stem cells (human ES cells), and induced pluripotent stem cells (iPS cells) created from adult human skin.